Multi-Scale Target-Aware Representation Learning for Fundus Image Enhancement

High-quality fundus images provide essential anatomical information for clinical screening and ophthalmic disease diagnosis. Yet, due to hardware limitations, operational variability, and patient compliance, fundus images often suffer from low resolution and signal-to-noise ratio. Recent years have witnessed promising progress in fundus image enhancement. However, existing works usually focus on restoring structural details or global characteristics of fundus images, lacking a unified image enhancement framework to recover comprehensive multi-scale information. Moreover, few methods pinpoint the target of image enhancement, e.g., lesions, which is crucial for medical image-based diagnosis. To address these challenges, we propose a multi-scale target-aware representation learning framework (MTRL-FIE) for efficient fundus image enhancement. Specifically, we propose a multi-scale feature encoder (MFE) that employs wavelet decomposition to embed both low-frequency structural information and high-frequency details. Next, we design a structure-preserving hierarchical decoder (SHD) to fuse multi-scale feature embeddings for real fundus image restoration. SHD integrates hierarchical fusion and group attention mechanisms to achieve adaptive feature fusion while retaining local structural smoothness. Meanwhile, a target-aware feature aggregation (TFA) module is used to enhance pathological regions and reduce artifacts. Experimental results on multiple fundus image datasets demonstrate the effectiveness and generalizability of MTRL-FIE for fundus image enhancement. Compared to state-of-the-art methods, MTRL-FIE achieves superior enhancement performance with a more lightweight architecture. Furthermore, our approach generalizes to other ophthalmic image processing tasks without supervised fine-tuning, highlighting its potential for clinical applications.

Transferable Adversarial Attacks on Black-Box Vision-Language Models

Vision Large Language Models (VLLMs) are increasingly deployed to offer advanced capabilities on inputs comprising both text and images. While prior research has shown that adversarial attacks can transfer from open-source to proprietary black-box models in text-only and vision-only contexts, the extent and effectiveness of such vulnerabilities remain underexplored for VLLMs. We present a comprehensive analysis demonstrating that targeted adversarial examples are highly transferable to widely-used proprietary VLLMs such as GPT-4o, Claude, and Gemini. We show that attackers can craft perturbations to induce specific attacker-chosen interpretations of visual information, such as misinterpreting hazardous content as safe, overlooking sensitive or restricted material, or generating detailed incorrect responses aligned with the attacker's intent. Furthermore, we discover that universal perturbations -- modifications applicable to a wide set of images -- can consistently induce these misinterpretations across multiple proprietary VLLMs. Our experimental results on object recognition, visual question answering, and image captioning show that this vulnerability is common across current state-of-the-art models, and underscore an urgent need for robust mitigations to ensure the safe and secure deployment of VLLMs.

Innovative Integration of 4D Cardiovascular Reconstruction and Hologram: A New Visualization Tool for Coronary Artery Bypass Grafting Planning

Background: Coronary artery bypass grafting (CABG) planning requires advanced spatial visualization and consideration of coronary artery depth, calcification, and pericardial adhesions. Objective: To develop and evaluate a dynamic cardiovascular holographic visualization tool for preoperative CABG planning. Methods: Using 4D cardiac computed tomography angiography data from 14 CABG candidates, we developed a semi-automated workflow for time-resolved segmentation of cardiac structures, epicardial adipose tissue (EAT), and coronary arteries with calcium scoring. The workflow incorporated methods for cardiac segmentation, coronary calcification quantification, visualization of coronary depth within EAT, and pericardial adhesion assessment through motion analysis. Dynamic cardiovascular holograms were displayed using the Looking Glass platform. Thirteen cardiac surgeons evaluated the tool using a Likert scale. Additionally, pericardial adhesion scores from holograms of 21 patients (including seven undergoing secondary cardiac surgeries) were compared with intraoperative findings. Results: Surgeons rated the visualization tool highly for preoperative planning utility (mean Likert score: 4.57/5.0). Hologram-based pericardial adhesion scoring strongly correlated with intraoperative findings (r=0.786, P<0.001). Conclusion: This study establishes a visualization framework for CABG planning that produces clinically relevant dynamic holograms from patient-specific data, with clinical feedback confirming its effectiveness for preoperative planning.

VistaDepth: Frequency Modulation With Bias Reweighting For Enhanced Long-Range Depth Estimation

Monocular depth estimation (MDE) aims to predict per-pixel depth values from a single RGB image. Recent advancements have positioned diffusion models as effective MDE tools by framing the challenge as a conditional image generation task. Despite their progress, these methods often struggle with accurately reconstructing distant depths, due largely to the imbalanced distribution of depth values and an over-reliance on spatial-domain features. To overcome these limitations, we introduce VistaDepth, a novel framework that integrates adaptive frequency-domain feature enhancements with an adaptive weight-balancing mechanism into the diffusion process. Central to our approach is the Latent Frequency Modulation (LFM) module, which dynamically refines spectral responses in the latent feature space, thereby improving the preservation of structural details and reducing noisy artifacts. Furthermore, we implement an adaptive weighting strategy that modulates the diffusion loss in real-time, enhancing the model's sensitivity towards distant depth reconstruction. These innovations collectively result in superior depth perception performance across both distance and detail. Experimental evaluations confirm that VistaDepth achieves state-of-the-art performance among diffusion-based MDE techniques, particularly excelling in the accurate reconstruction of distant regions.

RAID: An In-Training Defense against Attribute Inference Attacks in Recommender Systems

In various networks and mobile applications, users are highly susceptible to attribute inference attacks, with particularly prevalent occurrences in recommender systems. Attackers exploit partially exposed user profiles in recommendation models, such as user embeddings, to infer private attributes of target users, such as gender and political views. The goal of defenders is to mitigate the effectiveness of these attacks while maintaining recommendation performance. Most existing defense methods, such as differential privacy and attribute unlearning, focus on post-training settings, which limits their capability of utilizing training data to preserve recommendation performance. Although adversarial training extends defenses to in-training settings, it often struggles with convergence due to unstable training processes. In this paper, we propose RAID, an in-training defense method against attribute inference attacks in recommender systems. In addition to the recommendation objective, we define a defensive objective to ensure that the distribution of protected attributes becomes independent of class labels, making users indistinguishable from attribute inference attacks. Specifically, this defensive objective aims to solve a constrained Wasserstein barycenter problem to identify the centroid distribution that makes the attribute indistinguishable while complying with recommendation performance constraints. To optimize our proposed objective, we use optimal transport to align users with the centroid distribution. We conduct extensive experiments on four real-world datasets to evaluate RAID. The experimental results validate the effectiveness of RAID and demonstrate its significant superiority over existing methods in multiple aspects.

FairEval: Evaluating Fairness in LLM-Based Recommendations with Personality Awareness

Recent advances in Large Language Models (LLMs) have enabled their application to recommender systems (RecLLMs), yet concerns remain regarding fairness across demographic and psychological user dimensions. We introduce FairEval, a novel evaluation framework to systematically assess fairness in LLM-based recommendations. FairEval integrates personality traits with eight sensitive demographic attributes,including gender, race, and age, enabling a comprehensive assessment of user-level bias. We evaluate models, including ChatGPT 4o and Gemini 1.5 Flash, on music and movie recommendations. FairEval's fairness metric, PAFS, achieves scores up to 0.9969 for ChatGPT 4o and 0.9997 for Gemini 1.5 Flash, with disparities reaching 34.79 percent. These results highlight the importance of robustness in prompt sensitivity and support more inclusive recommendation systems.

Distilling Textual Priors from LLM to Efficient Image Fusion

Multi-modality image fusion aims to synthesize a single, comprehensive image from multiple source inputs. Traditional approaches, such as CNNs and GANs, offer efficiency but struggle to handle low-quality or complex inputs. Recent advances in text-guided methods leverage large model priors to overcome these limitations, but at the cost of significant computational overhead, both in memory and inference time. To address this challenge, we propose a novel framework for distilling large model priors, eliminating the need for text guidance during inference while dramatically reducing model size. Our framework utilizes a teacher-student architecture, where the teacher network incorporates large model priors and transfers this knowledge to a smaller student network via a tailored distillation process. Additionally, we introduce spatial-channel cross-fusion module to enhance the model's ability to leverage textual priors across both spatial and channel dimensions. Our method achieves a favorable trade-off between computational efficiency and fusion quality. The distilled network, requiring only 10\% of the parameters and inference time of the teacher network, retains 90\% of its performance and outperforms existing SOTA methods. Extensive experiments demonstrate the effectiveness of our approach. The implementation will be made publicly available as an open-source resource.

A Neuro-inspired Interpretation of Unlearning in Large Language Models through Sample-level Unlearning Difficulty

Driven by privacy protection laws and regulations, unlearning in Large Language Models (LLMs) is gaining increasing attention. However, current research often neglects the interpretability of the unlearning process, particularly concerning sample-level unlearning difficulty. Existing studies typically assume a uniform unlearning difficulty across samples. This simplification risks attributing the performance of unlearning algorithms to sample selection rather than the algorithm's design, potentially steering the development of LLM unlearning in the wrong direction. Thus, we investigate the relationship between LLM unlearning and sample characteristics, with a focus on unlearning difficulty. Drawing inspiration from neuroscience, we propose a Memory Removal Difficulty ($\mathrm{MRD}$) metric to quantify sample-level unlearning difficulty. Using $\mathrm{MRD}$, we analyze the characteristics of hard-to-unlearn versus easy-to-unlearn samples. Furthermore, we propose an $\mathrm{MRD}$-based weighted sampling method to optimize existing unlearning algorithms, which prioritizes easily forgettable samples, thereby improving unlearning efficiency and effectiveness. We validate the proposed metric and method using public benchmarks and datasets, with results confirming its effectiveness.

Bridging the Gap Between Preference Alignment and Machine Unlearning

Despite advances in Preference Alignment (PA) for Large Language Models (LLMs), mainstream methods like Reinforcement Learning with Human Feedback (RLHF) face notable challenges. These approaches require high-quality datasets of positive preference examples, which are costly to obtain and computationally intensive due to training instability, limiting their use in low-resource scenarios. LLM unlearning technique presents a promising alternative, by directly removing the influence of negative examples. However, current research has primarily focused on empirical validation, lacking systematic quantitative analysis. To bridge this gap, we propose a framework to explore the relationship between PA and LLM unlearning. Specifically, we introduce a bi-level optimization-based method to quantify the impact of unlearning specific negative examples on PA performance. Our analysis reveals that not all negative examples contribute equally to alignment improvement when unlearned, and the effect varies significantly across examples. Building on this insight, we pose a crucial question: how can we optimally select and weight negative examples for unlearning to maximize PA performance? To answer this, we propose a framework called Unlearning to Align (U2A), which leverages bi-level optimization to efficiently select and unlearn examples for optimal PA performance. We validate the proposed method through extensive experiments, with results confirming its effectiveness.

OmniCam: Unified Multimodal Video Generation via Camera Control

Camera control, which achieves diverse visual effects by changing camera position and pose, has attracted widespread attention. However, existing methods face challenges such as complex interaction and limited control capabilities. To address these issues, we present OmniCam, a unified multimodal camera control framework. Leveraging large language models and video diffusion models, OmniCam generates spatio-temporally consistent videos. It supports various combinations of input modalities: the user can provide text or video with expected trajectory as camera path guidance, and image or video as content reference, enabling precise control over camera motion. To facilitate the training of OmniCam, we introduce the OmniTr dataset, which contains a large collection of high-quality long-sequence trajectories, videos, and corresponding descriptions. Experimental results demonstrate that our model achieves state-of-the-art performance in high-quality camera-controlled video generation across various metrics.